One to One
David G. IosselianiInterventional Cardiologist, Professor, FACC, FESC, Director of Moscow City Center of Interventional Cardioangiology, Head Cardiologist of Moscow |
| Bleeding complications in the very elderly patients: trading off efficacy and safety regarding GPIIb/IIIa inhibitors and DES | I am not a partisan of GPIIb/IIIa inhibitors use in patients after PCI with stenting, especially in elderly ones. I would leave GPIIb/IIIa inhibitors only for the cases with valid, maybe even vital indications for their use, for example, acute vessel occlusion with the signs of acute thrombus formation. |
| How to measure quality of life in octogenarians and how this could interfere with treatment options? | The age itself doesn’t influence the choice of the method of treatment. However one has to consider existing comorbidities related to diffuse atherosclerotic process or other organs involvement. Then the preference should be given to a less traumatic and safer method. |
| The elderly patient with non-valvular AF: how to manage dual antiplatelet therapy after PCI with anticoagulation? | It is impossible to give a simple answer to this complex question, independently of all existing Guidelines and manuals. I believe that after PCI it is necessary to use Clopidogrel and Aspirin and withhold Warfarin for one month at least. After that one can continue Warfarin + Aspirin regimen. |
David G. Iosseliani